Perinatal (fetal and neonatal) choroid plexus tumors: a review

Control of Advanced Choroid Plexus Tumors

Immunohistochemical analysis of CDX2 expression in normal choroid plexus epithelium and choroid plexus tumors.

BACKGROUND The Wnt and BMP signaling pathways are involved in the morphogenesis of both gastrointestinal and choroid plexus epithelium. In the intestine, Wnt signaling represses the expression of the tumor suppressor gene CDX2 via SOX9, a transcription factor, which is also expressed in the choroid plexus. Recently, an inverse correlation between CDX2 expression and tumor grade, tumor stage and...

I-45: Choroid Plexus Cyst

CPCs are a relatively common finding during the second trimester sonography. when a choroid plexus cyst is identified, the presence of structural malformation and other sonographic markers of aneuploidy should be assessed with a detailed fetal anatomic survey performed by an experienced person. if no other sonographic abnormalities are present, the CPC is considered isolated. given the consider...

Neonatal choroid plexus cysts and early childhood developmental outcome.

BACKGROUND AND PURPOSE Choroid plexus cysts (CPCs) are incidental findings on sonograms of the neonatal head. The incidence of CPCs and their association with childhood neurodevelopmental outcome remains unclear. The purpose of this study was to determine the incidence of neonatal CPCs and their association with early childhood neurodevelopmental outcome. METHODS Between July 1997 and June 19...

Papillomas and carcinomas of the choroid plexus: histological and immunohistochemical studies and comparison with normal fetal choroid plexus.

BACKGROUND Choroid plexus tumors are rare. Results on immunohistochemical features are scanty and controversial even regarding normal plexus. METHOD Thirteen cases of choroid plexus tumors and five samples of normal fetal choroid plexus were submitted to immunohistochemical study using a panel of epithelial, neuronal and stromal markers. RESULTS/CONCLUSIONS Relevant histological findings we...